| Product name: |
Cleaved-KLK11 (I54) rabbit pAb |
| Reactivity: |
Human;Rat;Mouse; |
| Alternative Names: |
KLK11; PRSS20; TLSP; Kallikrein-11; hK11; Hippostasin; Serine protease 20; Trypsin-like protease |
| Source: |
Rabbit |
| Dilutions: |
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. |
| Immunogen: |
The antiserum was produced against synthesized peptide derived from human Kallikrein-11. AA range:35-84 |
| Storage: |
-20°C/1 year |
| Clonality: |
Polyclonal |
| Isotype: |
IgG |
| Concentration: |
1 mg/ml |
| Observed Band: |
25kD |
| GeneID: |
11012 |
| Human Swiss-Prot No: |
Q9UBX7 |
| Cellular localization: |
[Isoform 1]: Secreted.; [Isoform 2]: Golgi apparatus. |
| Background: |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009], |
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